Age-Related Macular Degeneration or AMD is one of the leading causes of vision loss of in people over the age of 50. This condition is painless, and occurs because small yellow waste deposits, known as drusen, accumulate in the macula. The macula is the central part of the retina, and is responsible for our sharpest and clearest vision. These drusen deposits result in damage to the macula, and lead to a loss of the central vision. The good news is that macular degeneration will not lead to total blindness. There are two forms of macular degeneration.